Author

Leona Gabryšová

ORCID 0000-0003-3529-1306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Anne O’Garra· 1 shared Catherine M. Hawrylowicz· 1 shared Charlotte Whicher· 1 shared Dimitrios Anastasiou· 1 shared Elizabeth H. Mann· 1 shared James I. MacRae· 1 shared Lydia Bradley· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Anne O’Garra

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1 paper

Recent·Most cited

Glycosylation-dependent modulation of the lL-2 signaling axis determines Th17 differentiation and IL-10 production

Leona Gabryšová, Elizabeth H. Mann, Lydia Bradley, James I. MacRae, Charlotte Whicher, Catherine M. Hawrylowicz, Dimitrios Anastasiou, Anne O’Garra

This study shows that 2-deoxyglucose modulates IL-2 signaling to influence Th17 differentiation and IL-10 production by inhibiting glycosylation rather than glycolysis.

bioRxiv · Mar 23, 2018 · PreprintImmunology