Author

Charushila Kumbhar

Indian Institute of Technology Bombay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

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Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ankita NagiD· 1 shared Sarika MehraiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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1 shared paperMicrobiology

Ankita NagORCID

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1 paper

Recent·Most cited

Adaptive Laboratory Evolution under gradual ciprofloxacin stress leads to efflux-mediated ciprofloxacin resistance and an increase in endogenous antibiotic production in Streptomyces coelicolor.

Ankita Nag, Charushila Kumbhar, Sarika Mehra

This study uses adaptive laboratory evolution to show that Streptomyces coelicolor develops ciprofloxacin resistance via efflux pumps and increased antibiotic production, with cross-resistance and collateral sensitivity to other drugs.

bioRxiv · Dec 22, 2025 · PreprintMicrobiology