Author

Chen Lian

Second Affiliated Hospital of Zhejiang University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alfredo RodrigueziD· 1 shared Boyu WangiD· 1 shared Hugo Sámano-Sánchez· 1 shared Jian LiuiD· 1 shared Jiayi Ran· 1 shared Junming LiiD· 1 shared Lian WangiD· 1 shared Manyu XiaoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alfredo RodriguezORCID

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1 paper

Recent·Most cited

A Non-Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zi Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Y Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, , Jian Liu

This study identifies SMAD4 as a regulator of 3D genome architecture in lung squamous cell carcinoma, showing its role in inhibiting tumor development by constraining chromatin looping.

Advanced Science · May 26, 2026Peer-reviewedCancer Biology