The MuSK-BMP pathway regulates synaptic Nav1.4 localization and muscle excitability
Lauren A. Fish, Madison D. Ewing, Kelly A. Rich, Chengjie Xi, Isabella Chen, Diego Jaime, Laura A. Madigan, Xueyong Wang, Justin L. Shahtout, R. E. Feder, Katsuhiko Funai, Jan L. Christian, Kristi A. Wharton, Mark M. Rich, William David Arnold, Justin R. Fallon
This study shows that the MuSK-BMP pathway regulates Nav1.4 localization and muscle excitability at the neuromuscular junction, with implications for congenital myasthenic syndromes and aging.
Journal of Neuroscience · Jan 29, 2025Peer-reviewedNeuroscience