Author

Laura A. Madigan

Brown UniversityORCID 0000-0002-5786-8420Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Justin R. FalloniD· 2 shared Alexander JaworskiiD· 1 shared Alexandra Weiss· 1 shared Alper KüçükuraliD· 1 shared Chengjie Xi· 1 shared Diane LipscombeiD· 1 shared Diego JaimeiD· 1 shared Emma M. ShychuckiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Justin R. FallonORCID

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2 papers

Recent·Most cited

NeuroscienceJournal of NeurosciencePeer-reviewedJan 29, 2025

The MuSK-BMP pathway regulates synaptic Nav1.4 localization and muscle excitability

Lauren A. Fish, Madison D. Ewing, Kelly A. Rich…·Justin R. Fallon

This study shows that the MuSK-BMP pathway regulates Nav1.4 localization and muscle excitability at the neuromuscular junction, with implications for congenital myasthenic syndromes and aging.

6 citations

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 5, 2023

Up-regulation of cholesterol synthesis pathways and limited neurodegeneration in a knock-in Sod1 mutant mouse model of ALS.

Janice A. Dominov, Laura A. Madigan, Joshua P. Whitt…·Robert H. Brown

This study shows that Sod1G85R knock-in mice exhibit up-regulated cholesterol synthesis pathways and limited neurodegeneration, contrasting with severe TgSOD1G93A mice, suggesting lipid pathway dysregulation in ALS.

7 citations

mousebulk RNA-seq

𝕏 PostBluesky