Oocyte-stored Mif promotes preimplantation development as an embryonic extracellular signal
John Xiao He Li, Huasong Wang, Lifang Li, Tursunjan Aziz, Huiying Huang, Chenxin Li, Guangyuan Li, Han Li, Jie Li, Lu Tian, Zihang Wei, Tianyi Zhang, Tong Zhu, Yuling Chen, Haiteng Deng, , Anming Meng
This study identifies Mif as an oocyte-stored protein that promotes preimplantation embryo development through extracellular signaling, showing its role in blastocyst growth and density-dependent effects.
bioRxiv · Nov 4, 2026 · PreprintDevelopmental Biology