Haiteng Deng

This study identifies Mif as an oocyte-stored protein that promotes preimplantation embryo development through extracellular signaling, showing its role in blastocyst growth and density-dependent effects.

The paper identifies eIF1A methylation sites and shows that methylation at R13 and R14 improves start codon recognition fidelity in yeast.

The paper identifies an IFN response-high epigenetic program linked to BAP1 deficiency in kidney cancer using single nucleus ATAC sequencing across multiple cohorts.

This study identifies lipid mono-unsaturation as a mechanism for cold tolerance in frogs and shows its potential to improve tissue viability during hypothermic storage.

This study identifies TMED proteins as key regulators of vesicle-dependent unconventional secretion, showing they mediate cargo selectivity through translocation and oligomerization.

This study shows that protein S-glutathionylation protects cells from ferroptosis by maintaining ARF6 function and reducing labile iron pools.

The paper identifies a unique mechanism by which ASXL1 K351 monoubiquitination enhances PR-DUB activity through structural stabilization, enabling efficient H2AK119Ub deubiquitination.

This study identifies RAS-induced non-canonical autophagy mediated by the P38-ULK1-PI4KB axis, showing its role in tumor growth and suggesting therapeutic targeting.

This study shows that co-transcriptional RNA processing via the CTD of Pol II is essential for zygotic gene activation, as disrupting it halts mRNA synthesis and increases noncoding RNA levels.

The paper develops Quartet, a proteome reference material with built-in truths, to assess label-free proteomics reproducibility across platforms and labs.

The paper introduces a pipeline called CHAMPION that uses qXL-MS and MONET modulomics to identify nuclear protein interactions and modules, revealing novel interactors and hormone-specific variants.

This paper introduces RiboCode, a method for de novo translatome annotation using ribosome profiling data, showing improved efficiency, sensitivity, and accuracy in identifying novel ORFs across different yeast stress conditions.