A Pan-Cancer Single-Cell Atlas to Evaluate Tumor Identity, Cell Line Concordance, and Dependency Mapping
Rosyli F. Reveron‐Thornton, James Paul Agolia, Chuner Guo, Maria Moozhiyil Korah, Chia-Hsin Hsu, Peter Y. Xie, Renceh A. B. Flojo, Andrea E. Delitto, Amanda Gonçalves, Angela D Tabora, Michael Januszyk, Victoria E Sanchez, Kevin Nee, Biren Reddy, Wesley Bobst, , Daniel Delitto
The paper constructs a pan-cancer single-cell atlas to improve tumor identity inference and identify genetic vulnerabilities by integrating high-quality malignant cells across multiple cancers.
bioRxiv · Feb 24, 2026 · PreprintCancer Biology