Quantitative dissection of the metastatic cascade at single colony resolution
Rui Tang, Chris Roberts, Andy Xu, Xiangwei Fang, Adrienne V. Visani, Chien-Wei Peng, Xulei Qin, Irenaeus C.C. Chan, Madeline Dunterman, David A. Giles, Yanhui You, Isabella Guppy, Zhang Yang, Timothy Woodiwiss, Albert H. Kim, , Li Ding
This paper introduces MOBA-seq, a platform to map genetic regulators of metastasis at single-colony resolution, identifying tissue-specific suppressors and universal essential genes.
bioRxiv · Sep 14, 2026 · PreprintCancer Biology