Author

David A. Giles

Washington University in St. LouisORCID 0000-0002-2745-4374Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:clustering· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Adrienne V. VisaniiD· 1 shared Albert H. KimiD· 1 shared Alexander Stegh· 1 shared Amjad HoraniiD· 1 shared Andy XuiD· 1 shared Chien-Wei Peng· 1 shared Chris Roberts· 1 shared Dakota DeFreitas· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Adrienne V. VisaniORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Quantitative dissection of the metastatic cascade at single colony resolution

Rui Tang, Chris Roberts, Andy Xu, Xiangwei Fang, Adrienne V. Visani, Chien-Wei Peng, Xulei Qin, Irenaeus C.C. Chan, Madeline Dunterman, David A. Giles, Yanhui You, Isabella Guppy, Zhang Yang, Timothy Woodiwiss, Albert H. Kim, , Li Ding

This paper introduces MOBA-seq, a platform to map genetic regulators of metastasis at single-colony resolution, identifying tissue-specific suppressors and universal essential genes.

bioRxiv · Sep 14, 2026 · PreprintCancer Biology

Cilia dysfunction in the lateral ventricles after neonatal intraventricular hemorrhage does not lead to functional changes in cilia-based CSF flow networks

Shelei Pan, Sruthi Ramagiri, Lihua Yang, David A. Giles, Isabella Xu, Maria Garcia Bonilla, Dakota DeFreitas, Lillian W. Siderowf, Grace L. Halupnik, Shriya Koneru, Gretchen M. Koller, Srinandan Polavarapu, Deepesh Kumar Gupta, Praveen Krishnamoorthy, Mark J. Miller, , Jennifer Mae Strahle

This study shows IVH reduces ciliated ependymal cells but does not disrupt cilia function or CSF flow networks in the lateral ventricles.

bioRxiv · Nov 3, 2024 · PreprintNeuroscience