Fat cadherin cleavage releases a transcriptionally active nuclear fragment to regulate target gene expression
Jannette Rusch, Nattapon Thanintorn, Chikin Kuok, Yonit Tsatskis, Huayun Hou, Michael D. Wilson, Cole R. Julick, Helen McNeill
The paper shows that the nuclear fragment of fat cadherin, generated by cleavage, regulates gene expression by interacting with Hippo pathway components and other factors.
bioRxiv · May 8, 2025 · PreprintDevelopmental Biology