Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases
Shih‐Wen Huang, Yein‐Gei Lai, Hao-Ting Liao, Chin-Ling Chang, Ruo-Yu Ma, Yung‐Hsiang Chen, Yae-Huei Liou, Zhenqi Wu, Yu-Chen Wu, Ko‐Jiunn Liu, Yen‐Tsung Huang, Jen-Lung Yang, Ming‐Shen Dai, Nan‐Shih Liao
This study shows that autologous NK cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases in a mouse model and a clinical trial.
eLife · Jun 19, 2024Peer-reviewedImmunology