Hippocampal engram networks for fear memory recruit new synapses and modify pre-existing synapses in vivo.
Chaery Lee, Byung Hun Lee, Hyunsu Jung, Chiwoo Lee, Yongmin Sung, Hyopil Kim, Jooyoung Kim, Jae Youn Shim, Ji‐il Kim, Dong Il Choi, Hye Yoon Park, Bong‐Kiun Kaang
This study tracks synaptic changes in the hippocampus during fear memory formation and extinction, showing synaptogenesis and synapse modification between CA3 and CA1 engram cells.
Current Biology · Jan 12, 2023Peer-reviewedNeuroscience