Hye Yoon Park

This study develops an optimized Nano-QuIC platform to detect alpha-synuclein oligomers in human plasma with high sensitivity for early Parkinson's disease diagnosis.

This study uses live-cell imaging to show that 10 Hz electrical stimulation maximizes Arc transcription and correlates with calcium transients, but calcium alone does not fully explain Arc induction.

This paper introduces Nano-QuIC, a method that improves the detection of misfolded α-synuclein in blood samples from Parkinson's patients compared to traditional RT-QuIC.

This study tracks synaptic changes in the hippocampus during fear memory formation and extinction, showing synaptogenesis and synapse modification between CA3 and CA1 engram cells.

The paper uses a genetically-encoded RNA indicator to visualize Arc mRNA dynamics in live animals during memory formation and retrieval, revealing rapid turnover in hippocampal neurons and stable expression in retrosplenial cortex neurons.

The paper introduces G-FISH, a method for RNA detection in FFPE tissues, and demonstrates its ability to detect specific RNAs in mouse brain and tumor tissues with high sensitivity and low background.