Discovery of cyclic peptide natural product inhibitors of Balamuthia mandrillaris
Chenyang Lu, Samantha L. Nelson, Gabriela Coy, Chris Neumann, Elizabeth I. Parkinson, Christopher A. Rice
This study evaluates cyclic peptides as inhibitors of Balamuthia mandrillaris, finding eight compounds with IC50 <5 μM and minimal cytotoxicity.
Journal of Natural Products · Feb 13, 2025Peer-reviewedPharmacology & Toxicology