Macrophage-derived RNAseT2 stimulates muscle stem cell fusion via SLK/N-WASP/actin bundling
Michèle Weiss‐Gayet, Gaëtan Juban, Emméran Le Moal, Antonio Moretta, Camilla Farnetani, Christelle Gobet, Jules Guillemaud, Marie‐Catherine Le Bihan, Oded Shoseyov, Annie Adrait, Katharina Ternka, Odile Boespflug‐Tanguy, Matthias Kettwig, Yohann Couté, Rémi Mounier, , Bénédicte Chazaud
This study identifies RNAseT2 as a macrophage-derived factor that promotes muscle stem cell fusion through SLK/N-WASP/actin bundling in mouse and zebrafish.
Nature Communications · Apr 14, 2026Peer-reviewedCell Biology