Bénédicte Chazaud

This study shows that neuromuscular electrical stimulation (NMES) reduces muscle weakness and atrophy, improves muscle stem cell function, and modulates inflammation in a mouse model of cancer cachexia.

This study identifies RNAseT2 as a macrophage-derived factor that promotes muscle stem cell fusion through SLK/N-WASP/actin bundling in mouse and zebrafish.

This study identifies defective muscle stem cell plasticity in dermatomyositis patients, linked to chronic inflammation and disrupted H3.3 chromatin loading, impairing myogenesis.

This paper shows that delivering AMPK activator 991 via polymeric nanoparticles reduces toxicity and improves muscle homeostasis in a DMD mouse model.

This study identifies that immune aging impairs muscle regeneration by altering macrophage-derived antioxidant selenoprotein P expression and function in aged mice.

This study shows that skeletal muscle stem cells modulate their niche in Duchenne muscular dystrophy via the YY1-CCL5 axis, influencing macrophage and fibro-adipogenic progenitor behavior and offering a therapeutic target.

The paper shows that human muscle fibroblasts and stem cells stimulate motor neuron growth and viability, with effects enhanced by exercise and mitigated by age.

The paper investigates how epigenetic changes in muscle stem cells from Duchenne Muscular Dystrophy patients lead to loss of myogenic identity and identifies MEF2B as a key mediator.