Author

Christian D Huber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Bernard Y Kim· 2 shared Kirk E Lohmueller· 2 shared Clare D Marsden· 1 shared

Activity by Year

2016-2016 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersEvolutionary Biology

Bernard Y Kim

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Evolutionary BiologybioRxivAug 25, 2016

Inference of the distribution of selection coefficients for new nonsynonymous mutations using large samples

Bernard Y Kim, Christian D Huber, Kirk E Lohmueller

This study estimates the distribution of selection coefficients for new nonsynonymous mutations using large datasets, finding fewer strongly deleterious and more weakly deleterious mutations than previous estimates.

DOI 10.1534/genetics.116.197145

humanwhole-exome sequencing

𝕏 PostBluesky

Evolutionary BiologybioRxivAug 23, 2016

Determining the factors driving selective effects of new nonsynonymous mutations

Christian D Huber, Bernard Y Kim, Clare D Marsden, Kirk E Lohmueller

The paper compares theoretical models of mutation effects and finds that Fisher's Geometrical Model best explains the distribution of fitness effects in humans compared to Drosophila melanogaster.

DOI 10.1073/pnas.1619508114

humanDrosophila

𝕏 PostBluesky