Functional characterization of Polr3a hypomyelinating leukodystrophy mutations in the S. cerevisiae homolog, RPC160.
Robyn D. Moir, Christian Lavados, Jae Hoon Lee, Ian M. Willis
The paper evaluates the functional impact of Polr3a mutations associated with hypomyelinating leukodystrophy by engineering them into the yeast homolog Rpc160 and analyzing their effects on transcription.
Gene · Oct 23, 2020Peer-reviewedMolecular Biology