Genomic epidemiology of the current wave of artemisinin resistant malaria
Roberto Amato, Olivo Miotto, Charles Woodrow, Jacob Almagro-Garcia, Ipsita Sinha, Susana Campino, Daniel Mead, Eleanor Drury, Mihir Kekre, Mandy Sanders, Alfred Amambua-Ngwa, Chanaki Amaratunga, Lucas Amenga-Etego, Tim J C Anderson, Voahangy Andrianaranjaka, , MalariaGEN Plasmodium falciparum Community Project
This study identifies kelch13 mutations associated with artemisinin resistance in Southeast Asia and finds low frequency of these mutations in Africa, suggesting different evolutionary pressures.
bioRxiv · May 24, 2015 · PreprintEvolutionary Biology