Author

Christina E. Boville

California Institute of Technology

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Synthetic Biology· 1

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Approach:experimental assay· 1

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Chang C. LiuiD· 1 shared Ella J. Watkins‐DulaneyiD· 1 shared Frances H. ArnoldiD· 1 shared Gordon RixiD· 1 shared Patrick J. AlmhjelliD· 1 shared

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1 shared paperSynthetic Biology

Chang C. LiuORCID

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Synthetic BiologyNature CommunicationsPeer-reviewedNov 6, 2020

Scalable, continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities

Gordon Rix, Ella J. Watkins‐Dulaney, Patrick J. Almhjell…·Chang C. Liu

This paper develops a continuous directed evolution platform called OrthoRep to generate diverse enzyme variants with promiscuous activities by evolving TmTrpB through multi-mutation pathways.

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experimental assay

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