Christina Rabeler

Modulation of planarian seizure-like activity via antiseizure medications

The paper tests antiseizure medications on planarians to assess their ability to reduce seizure-like activity caused by neurotoxic compounds.

Planarian behavioral screening is a useful invertebrate model for evaluating seizurogenic chemicals

This study evaluates the use of planarians as a model for detecting seizurogenic chemicals, showing that several mammalian seizurogens induce seizure-like behavior in two planarian species.

Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians

This paper classifies neuroactive drugs using computational physicochemical properties and planarian behavioral profiling, finding both methods are accurate, with planarian testing adding value for multi-use drugs.