ImmunologybioRxivPreprint
Insulin-binding B cells can arise in early-stage type 1 diabetes individuals in the absence of somatic hypermutation or insulin autoantibody seropositivity
Lindsay E Bass, Tommi C Taylor, Mason V Forchetti…·Rachel H. Bonami
The paper identifies anti-insulin B cells in early-stage T1D patients without autoantibodies or somatic hypermutation, showing their role in autoimmunity.