Christine M.W. Lum

Maternal high fat diet alters lactation-specific miRNA expression and programs the DNA methylome in the amygdala of female offspring

This study shows that maternal high fat diet reduces lactation-specific miRNAs in milk and amygdala, leading to increased DNA methylation and altered neurodevelopmental pathways in female offspring.

Maternal high-fat diet induces sex-specific changes to glucocorticoid and inflammatory signaling in response to corticosterone and lipopolysaccharide challenge in adult rat offspring

This study shows that maternal high-fat diet leads to sex-specific changes in inflammatory and glucocorticoid signaling in adult rat offspring under stress and immune challenges.