Patrick O. McGowan

The paper compares methods for milk pre-processing, exosome isolation, and RNA extraction in bovine and human milk, finding that pre-processing does not improve exosome yield, ExoQuick is better for isolation, and TRIzol LS provides highest RNA yield in bovine milk.

This study examines how early-life temperature exposure impacts thyroid hormone receptor signaling and DNA methylation in female rat pups, linking these changes to epigenetic regulation in the paraventricular nucleus.

This study shows that maternal high fat diet reduces lactation-specific miRNAs in milk and amygdala, leading to increased DNA methylation and altered neurodevelopmental pathways in female offspring.

This study shows that maternal high-fat diet leads to sex-specific changes in inflammatory and glucocorticoid signaling in adult rat offspring under stress and immune challenges.

The paper investigates how dopamine genotype interacts with early-life maternal care to influence later-life maternal care provisioning in female rat offspring.

This study identifies genetic and epigenetic interactions associated with ME/CFS by analyzing DNA methylation and SNP variability in patients and healthy controls.