Sanoji Wijenayake

This study shows that maternal stress during lactation alters milk-derived extracellular vesicle miRNAs, which affect offspring hippocampal gene expression, and that environmental enrichment can reverse these effects.

This study shows that human milk-derived extracellular vesicles enhance the heat shock response in polarized microglia, promoting proteostasis and pro-survival effects.

This study shows that milk-derived extracellular vesicles reduce NF-κB pathway and NLRP3 inflammasome activation in neonatal rats exposed to maternal high fat diet.

This study shows that milk-derived extracellular vesicles enhance the heat shock response in female neonatal rats exposed to maternal high-fat diets, particularly in the prefrontal cortex.

This study validates polarization biomarkers for human microglia (HMC3) using RT-qPCR, providing a comprehensive list of markers and methodology for gene expression analysis.

The paper compares methods for milk pre-processing, exosome isolation, and RNA extraction in bovine and human milk, finding that pre-processing does not improve exosome yield, ExoQuick is better for isolation, and TRIzol LS provides highest RNA yield in bovine milk.

This study shows that maternal high fat diet reduces lactation-specific miRNAs in milk and amygdala, leading to increased DNA methylation and altered neurodevelopmental pathways in female offspring.

This study shows that maternal high-fat diet leads to sex-specific changes in inflammatory and glucocorticoid signaling in adult rat offspring under stress and immune challenges.