Author

Aya Sasaki

University of TorontoORCID 0000-0001-8770-1341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:multiome· 1 Organism:rat· 1

Frequent Co-Authors

Christine M.W. Lum· 2 shared Patrick O. McGowaniD· 2 shared Sanoji WijenayakeiD· 2 shared Wilfred C. de Vega· 2 shared Mouly F. RahmaniD· 1 shared Sameera AbuaishiD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 14 mutual co-author links

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2 shared papersMolecular Biology

Christine M.W. Lum

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 13, 2020

Maternal high fat diet alters lactation-specific miRNA expression and programs the DNA methylome in the amygdala of female offspring

Sameera Abuaish, Sanoji Wijenayake, Wilfred C. de Vega…·Patrick O. McGowan

This study shows that maternal high fat diet reduces lactation-specific miRNAs in milk and amygdala, leading to increased DNA methylation and altered neurodevelopmental pathways in female offspring.

6 citations

mouseDNA methylation

𝕏 PostBluesky

NeuroscienceJournal of NeuroinflammationPeer-reviewedApr 15, 2020

Maternal high-fat diet induces sex-specific changes to glucocorticoid and inflammatory signaling in response to corticosterone and lipopolysaccharide challenge in adult rat offspring

Sanoji Wijenayake, Mouly F. Rahman, Christine M.W. Lum…·Patrick O. McGowan

This study shows that maternal high-fat diet leads to sex-specific changes in inflammatory and glucocorticoid signaling in adult rat offspring under stress and immune challenges.

27 citations

ratbulk RNA-seq

𝕏 PostBluesky