A chemical strategy to control protein networks in vivo
Michael J. Ziegler, Klaus Yserentant, Valentin Dunsing, Volker Middel, Antoni J. Gralak, Kaisa Pakari, Jörn Bargstedt, Christoph Kern, Annett Petrich, Salvatore Chiantia, Uwe Strähle, Dirk‐Peter Herten, Richard Wombacher
This paper introduces Mandi, a novel chemical inducer of protein proximity, and demonstrates its use in cell culture and living organisms for protein manipulation.
Nature Chemical Biology · Dec 21, 2021Peer-reviewedSynthetic Biology