Uwe Strähle

This study shows that Bbs1 is essential for maintaining photoreceptor outer segment lipid composition and function, with loss leading to early visual deficits and retinal degeneration.

This paper introduces Mandi, a novel chemical inducer of protein proximity, and demonstrates its use in cell culture and living organisms for protein manipulation.

This study identifies BMP/Id1 signaling as critical for maintaining NSC quiescence and regenerative capacity in adult zebrafish telencephalon, with Her4.1 as a key downstream target.

The paper analyzes transcriptomic changes in zebrafish telencephalon after injury, revealing a coordinated switch in cholesterol metabolism involving multiple regulatory mechanisms.

The paper identifies a PSMC3 variant causing a neurosensory syndrome with deafness and cataracts due to proteotoxic stress and impaired proteasome function.

The paper identifies Pcdh18a-positive tip cells that guide notochord formation in zebrafish through migration and signaling.

The paper describes a Barhl1a:GFP reporter line in zebrafish showing Barhl1a expression in subsets of retinal ganglion cells and commissural neurons during development.

The paper identifies a conserved enhancer module regulating id1 expression in zebrafish neural stem cells, showing BMP signaling controls NSC quiescence and proliferation.