Author

Christopher A. Leppla

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Approach:machine learning (classical)· 1 Organism:rat· 1

Frequent Co-Authors

Anna BeyeleriD· 2 shared Craig P. Wildes· 2 shared Eyal Yaacov KimchiiD· 2 shared Gordon F. Glober· 2 shared Jacob M. OlsoniD· 2 shared Kay M. TyeiD· 2 shared Praneeth Namburi· 2 shared Amy K. Sutton· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Anna BeyelerORCID

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3 papers

Recent·Most cited

Adapt-A-Maze: An Open Source Adaptable and Automated Rodent Behavior Maze System

Blake S. Porter, Jacob M. Olson, Christopher A. Leppla, Éléonore Duvelle, John H. Bladon, Matthijs A. A. van der Meer, Shantanu P. Jadhav

The paper introduces an open-source, modular maze system for rodent behavior research that improves flexibility, automation, and experimental repeatability.

eNeuro · Jun 5, 2025Peer-reviewedNeuroscience

Thalamus sends information about arousal but not valence to the amygdala

Christopher A. Leppla, Laurel R. Keyes, Gordon F. Glober, Gillian A. Matthews, Kanha Batra, Maya Jay, Yu Feng, Hannah S. Chen, Fergil Mills, Jeremy Delahanty, Jacob M. Olson, Edward H. Nieh, Praneeth Namburi, Craig P. Wildes, Romy Wichmann, , Kay M. Tye

The paper investigates the role of the MGN-BLA circuit in associative learning, finding that the MGN encodes arousal but not valence, while the BLA encodes both.

Psychopharmacology · Dec 15, 2022Peer-reviewedNeuroscience

Acute Food Deprivation Rapidly Modifies Valence-Coding Microcircuits in the Amygdala

Gwendolyn G. Calhoon, Amy K. Sutton, Chia-Jung Chang, Avraham M. Libster, Gordon F. Glober, Clémentine L Lévêque, Grayson Murphy, Praneeth Namburi, Christopher A. Leppla, Cody A. Siciliano, Craig P. Wildes, Eyal Yaacov Kimchi, Anna Beyeler, Kay M. Tye

The paper shows that food deprivation rapidly shifts the balance between BLA neurons projecting to NAc and CeM, altering valence coding and reward motivation.

bioRxiv · Mar 19, 2018 · PreprintNeuroscience