A membrane-permeable small molecule biosensor accesses intractable cells and animals without genetic manipulation
Gabriel Kreider, Christopher J. MacNevin, Pothiappan Vairaprakash, Marie Rougié, Michael V. Tran, Jason J. Yi, Ewan James McGhee, Denis Tsygankov, Yoshikazu Ohno, Kurt Anderson, Klaus M. Hahn
The paper develops a membrane-permeable small molecule biosensor, CaMero, to detect calmodulin activation in cells and animals without genetic modification.
bioRxiv · May 28, 2026 · PreprintCell Biology