Treatment of Graft-versus-Host Disease by Echinomycin in a New Humanized Mouse Model
Yan Liu, Christopher Bailey, Christopher Lazarski, Chun-shu Wong, Pan Zheng, Yang Liu, Yin Wang
This study develops a new humanized GVHD model and shows that Echinomycin, a HIF1 inhibitor, reduces GVHD symptoms and extends survival in mice.
bioRxiv · Feb 16, 2017 · PreprintImmunology