Uncovering bacterial pseudaminylation with pan-specific antibody tools
Kristian I. Karlic, Arthur H. Tang, Niccolay Madiedo Soler, Leo Corcilius, Christopher Lehmann, Aleksandra W. Debowski, Ashleigh L. Dale, Lauren Zavan, Michelle Cielesh, Adedunmola P. Adewale, Karen D. Moulton, Lucy Qian Li, Chenzheng Guan, Maria Kaparakis‐Liaskos, Benjamin P. Howden, , Richard J. Payne
This study develops pan-specific monoclonal antibodies to detect pseudaminic acids in bacteria, enabling deeper glycoproteomic analysis and improved phagocytosis of multidrug-resistant strains.
bioRxiv · Jul 13, 2025 · PreprintBiochemistry