A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia
Lynsey S. Hall, Christopher William Medway, Oliver Pain, Antonio F. Pardiñas, Elliott Rees, Valentina Escott‐Price, Andrew J. Pocklington, Nicholas J. Bray, Peter Holmans, James Walters, Michael John Owen, Michael C. O’Donovan
This study performs a transcriptome-wide association study to link schizophrenia risk variants to gene expression in the dorsolateral prefrontal cortex, identifying 89 genes associated with pre- and post-synaptic abnormalities.
Human Molecular Genetics · Oct 23, 2019Peer-reviewedGenetics