Role of FYVE and Coiled-Coil Domain Autophagy Adaptor 1 in severity of COVID-19 infection: from GWAS hit to therapeutic hypothesis
Sandra Paulina Smieszek, Bartlomiej P. Przychodzen, Christos M. Polymeropoulos, Vasilios M. Polymeropoulos, Mihael H. Polymeropoulos
The paper identifies a genetic locus associated with severe COVID-19 and hypothesizes that downregulating FYCO1 with indomethacin may reduce viral replication and infectivity.
medRxiv · Jan 22, 2021 · PreprintGenetic & Genomic Medicine