PEBP1 is a candidate biomarker of response to the PP2A inhibitor LB-100
Matheus Henrique Dias, Chrysa Papagianni, René Bernards
This study identifies PEBP1 as a biomarker for response to the PP2A inhibitor LB-100, showing that its depletion confers resistance by reducing prodrug conversion to the active metabolite endothall.
bioRxiv · Feb 25, 2025 · PreprintCancer Biology