A latent hydrazone switch turns SP2509 into an optical timer of cell fate
Chuan-Shuo Wu, Li Liu, Liang Cheng
This paper demonstrates that SP2509, an LSD1 inhibitor, can be converted into an optical timer for cell fate regulation through a latent hydrazone switch that responds to light.
bioRxiv · Aug 4, 2026 · PreprintBiochemistry