Author

Liang Cheng

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Biochemistry· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Lishan SuiD· 2 shared Chuan-Shuo Wu· 1 shared Di WuiD· 1 shared Eric Van BureniD· 1 shared Feng LiiD· 1 shared Guangming LiiD· 1 shared Jerry Jeffrey· 1 shared Jianping MaiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenomics

Lishan SuORCID

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3 papers

Recent·Most cited

A latent hydrazone switch turns SP2509 into an optical timer of cell fate

Chuan-Shuo Wu, Li Liu, Liang Cheng

This paper demonstrates that SP2509, an LSD1 inhibitor, can be converted into an optical timer for cell fate regulation through a latent hydrazone switch that responds to light.

bioRxiv · Aug 4, 2026 · PreprintBiochemistry

TWO-SIGMA-G: A New Competitive Gene Set Testing Framework for scRNA-seq Data Accounting for Inter-Gene and Cell-Cell Correlation

Eric Van Buren, Ming Hu, Liang Cheng, John A. Wrobel, Kirk C. Wilhelmsen, Lishan Su, Yun Li, Di Wu

TWO-SIGMA-G tests gene sets in scRNA-seq data by accounting for gene and cell correlations, showing improved power and error control in simulations and real datasets.

Briefings in Bioinformatics · Feb 20, 2022Peer-reviewedGenomics

Specific activation of HIV-1 from monocytic reservoir cells by bromodomain inhibitor in humanized mice in vivo

Guangming Li, Zheng Zhang, Natalia Reszka-Blanco, Feng Li, Liqun Chi, Jianping Ma, Jerry Jeffrey, Liang Cheng, Lishan Su

This study shows that the bromodomain inhibitor I-BET151 activates HIV-1 transcription in monocytic cells but not CD4+ T cells under cART in humanized mice.

bioRxiv · Jul 24, 2018 · PreprintImmunology