Pharmacokinetics and Physiologically Based Pharmacokinetic Modeling of Mycobacteriophages: Insights into Pulmonary Distribution and Clearance
Rajnikant Sharma, Ramya Mahadevan, Sai Divyash, Shekhar Yeshwante, Saikumar Matcha, ChunFu Cheng, Hunter S. Talley, Alan A. Schmalstig, Pradeep Neupane, Sara E. Maloney, Anthony James Hickey, Graham F. Hatfull, Miriam Braunstein, Gauri G. Rao
The paper studies pharmacokinetics of mycobacteriophages in mice and develops a PBPK model to predict their distribution and clearance, showing that inhalation improves lung exposure.
Molecular Pharmaceutics · Sep 17, 2026Peer-reviewedPharmacology & Toxicology