Non-invasive detection of upper tract urothelial carcinomas through the analysis of driver gene mutations and aneuploidy in urine
Simeon Springer, Chung-Hsin Chen, Lu Li, Chris Douville, Yuxuan Wang, Josh Cohen, Bahman Afsari, Ludmila Danilova, Natalie Silliman, Joy Schaeffer, Janine Ptak, Lisa Dobbyn, Maria Papoli, Isaac Kinde, Chao-Yuan Huang, , Kathleen G. Dickman
This study develops a non-invasive test for upper tract urothelial carcinomas using urine-based molecular analysis of driver gene mutations and aneuploidy, showing high sensitivity compared to current methods.
bioRxiv · Oct 16, 2017 · PreprintCancer Biology