Competitive coordination of the dual roles of the Hedgehog co-receptor in homophilic adhesion and signal reception
Shu Yang, Ya Zhang, Chuxuan Yang, Xuefeng Wu, Sara El Oud, Rongfang Chen, Xudong Cai, Xufeng Wu, Ganhui Lan, Xiaoyan Zheng
The paper shows that Ihog's dual roles in homophilic adhesion and Hh signaling are functionally coordinated to facilitate Hh transport and reception along cytonemes.
eLife · May 10, 2021Peer-reviewedBioinformatics