NeuroscienceNeurobiology of DiseasePeer-reviewed
Characterization and validation of 16 α-synuclein conformation-specific antibodies using well-characterized preparations of α-synuclein monomers, fibrils and oligomers with distinct structures and morphology: How specific are the conformation-specific α-synuclein antibodies?
Senthil T. Kumar, Somanath Jagannath, Cindy François…·Hilal Ahmed Lashuel
The paper characterizes 16 α-synuclein conformation-specific antibodies using defined preparations of α-synuclein species, finding none are specific to a single species and many recognize fibrils as well as oligomers.
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