Crosslinking-mediated Interactome Analysis Identified PHD2-HIF1α Interaction Hotspots and the Role of PHD2 in Regulating Protein Neddylation
Haiping Ouyang, Cindy Y. How, Xiaorong Wang, Clinton Yu, Ang Luo, Lan Ji Huang, Yue Chen
This study identifies PHD2 interaction hotspots and reveals its role in regulating protein neddylation through interaction with the COP9 Signalosome complex.
bioRxiv · Dec 16, 2024 · PreprintBiochemistry