Author

Claes Paul

Vrije Universiteit Brussel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Anja HeymansiD· 1 shared Anneleen MortieriD· 1 shared Brendan P. NormaniD· 1 shared George Bou–GhariosiD· 1 shared Gigly G. Del’hayeiD· 1 shared Gunter LeuckxiD· 1 shared Haaike Colemonts‐VroninksiD· 1 shared James A. Gallagher· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Anja HeymansORCID

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1 paper

Recent·Most cited

Liver-directed AAV gene therapy metabolically corrects AKU in Hgd deficient mice

Sien Lequeue, Brendan P. Norman, Gigly G. Del’haye, Jessie Neuckermans, Haaike Colemonts‐Vroninks, Juliette H. Hughes, Matthias Rombaut, Claes Paul, Anja Heymans, Yves Heremans, Gunter Leuckx, Anneleen Mortier, Lakshminarayan R Ranganath, James A. Gallagher, Tamara Vanhaecke, , Joery De Kock

This study demonstrates that liver-directed AAV gene therapy corrects metabolic defects in Hgd-deficient mice by restoring HGD expression and reducing HGA levels without hypertyrosinemia.

bioRxiv · Jun 2, 2026 · PreprintGenetics