Functional study of two flexible regions of the hepatitis E virus ORF1 replicase
Léa Mézière, Sonia Fieulaine, Claire Montpellier, Martin Ferrié, Thibault Tubiana, Gabriel Vanegas Arias, Stéphane Bressanelli, Laurence Cocquerel, Cécile‐Marie Aliouat‐Denis
This study investigates two flexible regions of the HEV ORF1 replicase using structural modeling and mutagenesis, showing their functional importance in viral replication.
PLoS ONE · Mar 10, 2026Peer-reviewedMicrobiology