Metabolic labelling of RNA uncovers the contribution of transcription and decay rates on hypoxia-induced changes in RNA levels
María Tiana, Bárbara Acosta-Iborra, Rosana Hernández, Clara Galiana, Miguel Ángel Fernández‐Moreno, Benilde Jiménez, Luis del Peso
This study uses metabolic labeling to quantify how hypoxia affects RNA levels through transcription and decay rates, finding that transcription is the main driver but degradation also contributes significantly.
RNA · Apr 15, 2020Peer-reviewedMolecular Biology