A personalized, multi-omics approach identifies genes involved in cardiac hypertrophy and heart failure
Marc Santolini, Milagros C. Romay, Clara Yukhtman, Christoph D. Rau, Shuxun Vincent Ren, Jeffrey J. Saucerman, Jessica Wang, James N. Weiss, Yibin Wang, Aldons Jake Lusis, Alain Karma
The paper identifies disease-associated genes missed by traditional methods using a personalized differential gene expression analysis in a genetically diverse mouse model of cardiac hypertrophy and heart failure.
npj Systems Biology and Applications · Feb 20, 2018Peer-reviewedSystems Biology