Yibin Wang

This study identifies the IRE1-Xbp1-Vimp/Rpn2 axis as a regulator of differential growth between left and right ventricles during postnatal development by modulating cardiomyocyte proliferation, hypertrophy, and apoptosis.

The paper constructs a large-scale heart atlas and identifies cellular changes and communication patterns in aging and disease using a new computational method.

This study compares histological features of carotid plaques between Chinese and U.S. patients, finding differences in lipid pools, intraplaque hemorrhage, and fibrous cap disruptions.

This paper identifies DICAR-JP as a functional domain that interacts with NAC to regulate OGDHL nascent peptide expression and mitochondrial translocation, proposing a new theory of ribosome migration in diabetic cardiomyopathy.

The paper uses time-series spatial transcriptomics to study human cell grafts in pig hearts after myocardial infarction, identifying Midkine signaling as a key pathway for vascularization.

This study shows mitochondrial CaMKII activation leads to metabolic reprogramming, energetic insufficiency, and dilated cardiomyopathy, with potential therapeutic targets identified.

The paper identifies disease-associated genes missed by traditional methods using a personalized differential gene expression analysis in a genetically diverse mouse model of cardiac hypertrophy and heart failure.