Time-resolved mapping of genetic interactions to model rewiring of signaling pathways
Florian Heigwer, Christian Scheeder, Thilo Miersch, Barbara A. Schmitt, Claudia Blass, Mischan Vali Pour-Jamnani, Michael Boutros
The paper identifies time-dependent genetic interactions in Drosophila cells using RNAi screens and develops an algorithm to analyze rewiring of signaling pathways.
eLife · Dec 28, 2018Peer-reviewedGenomics