Pharmacological Macrophage Attenuation by Imatinib Reverts Hepatic Steatosis and Inflammation in Obese Mice
Shefaa AlAsfoor, Theresa V. Rohm, Angela J. T. Bosch, Thomas Dervos, Diego Calabrese, Matthias S. Matter, Achim Weber, Claudia Cavelti-Weder
This study shows imatinib reduces macrophage inflammation and improves NAFLD in obese mice, with potential for human application.
bioRxiv · Dec 30, 2017 · PreprintImmunology